Grease: The Original Soundtrack from the Motion Picture is the original motion picture soundtrack for the 1978 film Grease. It was originally released by RSO Records and subsequently re-issued by Polydor Records between 1984 and 1991. It has sold over 30 million copies worldwide, making it one of the best-selling albums of all time, also ranking amongst the biggest selling soundtrack albums of all time. The song "You're the One That I Want" was a US and UK No. 1 for stars John Travolta and Olivia Newton-John.

Besides performers John Travolta and Olivia Newton-John, the album also featured songs by rock and roll revival group Sha Na Na as well as the hit song "Grease", a tune written by Barry Gibb (of the Bee Gees) and sung by Frankie Valli (of The Four Seasons) that was an additional US number one.