A British actress, she began her career with the television series Cold Feet and War of the Worlds.

She gained wider recognition for her starring role in the miniseries Normal People, which earned her nominations for a British Academy Television Award and a Golden Globe Award.

In 2022, she starred in the comedy-thriller film Fresh, the commercially successful mystery film Where the Crawdads Sing, and the crime miniseries Under the Banner of Heaven. She received another Golden Globe nomination for Under the Banner of Heaven.

Edgar-Jones dove into big budget movies in 2024 with her starring role in Twisters