One day, a sudden invasion of a virus made up of particles known as the 'Chaos Header' invades the Earth, seeking to possess the monsters to manipulate them to destroy the Earth. Musashi Haruno, a member of Team EYES once again encounters the giant, Ultraman Cosmos after ten years, reuniting as one with a strong will to see the monsters and human live in harmony. Cosmos grants Musashi a special power that will allow him to heal the corrupted monsters, with Musashi's transformation into Cosmos unknown to the rest of the team.